
• Enrolled HIV serodiscordant couples in nine
countries (Botswana, Kenya, Malawi, South
Africa, Zimbabwe, Brazil, India, Thailand and
USA) starting in 2005
• CD4 count between 350 and 550 cells/mm
3
• Randomly assigned to immediate or delayed
antiretroviral treatment (started when two
CD4 count <250 cells/mm
3
or development of
an AIDS-defining illness)